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KMID : 0378119890160020447
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Chungnam Medical Journal
1989 Volume.16 No. 2 p.447 ~ p.451
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Clinical Study of the Recurrent Graves´ Disease after Antithyroid Drug Therapy
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Abstract
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Clinical differnece between 13 remitted and 9 non-remitted patients with Graves´ disease treated with antithyroid drug for about 2 years were analysed.
The results were as follows：
1. Mean duration of treatment between remission group (22.1± 2.28 months) and non-remission group (22.4± 4.19 months) were not significantly different (P > 0.1), and no difference for sex between groups.
2. Mean duration of normalization of goiter size in remission group (18.77± 2.18 months) was not significantly different from non-remission group (20.14± 4.25 months) (P > 0.1).
3. Serum TBII activity in Graves´ disease in remission (14.14± 5.79％) was higher than non-remitted Graves´ disease (9.49± 5.05％), but significant difference were not noted(P > 0.1).
4. Mean serum TSH value in non-remitted patients (0.19± 0.14μU/ml) was significantly lower than that of Graves´ disease in remission (1.39± 0.49μU/ml)(P < 0.05).
The above results indicate that there were no clinical difference between Graves´ disease in remission and non-remitted Graves´ disease except serum TSH value measured by IRMA, which is the most reliable index of estimating the prognosis.
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